Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

Cisplatin is an effective breast cancer drug but resistance often develops over prolonged chemotherapy. Therefore, we performed a candidate approach RNAi screen in combination with cisplatin treatment to identify molecular pathways conferring survival advantages. The screen identified ATP7A as a the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Chisholm, Cristine L., Wang, Haitao, Wong, Ada Hang-Heng, Vazquez-Ortiz, Guelaguetza, Chen, Weiping, Xu, Xiaoling, Deng, Chu-Xia
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341295/
https://ncbi.nlm.nih.gov/pubmed/27806319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12992
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker