Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

Cisplatin is an effective breast cancer drug but resistance often develops over prolonged chemotherapy. Therefore, we performed a candidate approach RNAi screen in combination with cisplatin treatment to identify molecular pathways conferring survival advantages. The screen identified ATP7A as a the...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chisholm, Cristine L., Wang, Haitao, Wong, Ada Hang-Heng, Vazquez-Ortiz, Guelaguetza, Chen, Weiping, Xu, Xiaoling, Deng, Chu-Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341295/
https://ncbi.nlm.nih.gov/pubmed/27806319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12992
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