Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

Cisplatin is an effective breast cancer drug but resistance often develops over prolonged chemotherapy. Therefore, we performed a candidate approach RNAi screen in combination with cisplatin treatment to identify molecular pathways conferring survival advantages. The screen identified ATP7A as a the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Chisholm, Cristine L., Wang, Haitao, Wong, Ada Hang-Heng, Vazquez-Ortiz, Guelaguetza, Chen, Weiping, Xu, Xiaoling, Deng, Chu-Xia
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341295/
https://ncbi.nlm.nih.gov/pubmed/27806319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12992
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