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Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells

BACKGROUND: Copper homeostasis proteins ATP7A and ATP7B are assumed to be involved in the intracellular transport of cisplatin. The aim of the present study was to assess the relevance of sub cellular localisation of these transporters for acquired cisplatin resistance in vitro. For this purpose, lo...

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Detalhes bibliográficos
Main Authors: Kalayda, Ganna V, Wagner, Christina H, Buß, Irina, Reedijk, Jan, Jaehde, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442842/
https://ncbi.nlm.nih.gov/pubmed/18565219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-175
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