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Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Antibody 34E4 catalyzes the conversion of benzisoxazoles to salicylonitriles with high rates and multiple turnovers. The crystal structure of its complex with the benzimidazolium hapten at 2.5-Å resolution shows that a combination of hydrogen bonding, π stacking, and van der Waals interactions is ex...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC555987/ https://ncbi.nlm.nih.gov/pubmed/15788533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409207102 |
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