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Tunnel plasticity and quaternary structural integrity of a pentameric protein ring

Cyclic protein oligomers are common in cells. However, the importance of the residues that line the central tunnel of protein rings for overall architectural integrity is not well understood. To investigate the role of tunnel positions in protein assembly and stability, we prepared variants of the h...

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Bibliographic Details
Main Authors: Woycechowsky, Kenneth J., Seebeck, Florian P., Hilvert, Donald
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242520/
https://ncbi.nlm.nih.gov/pubmed/16641488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052044606
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