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Pentameric quaternary structure of the intracellular domain of serotonin type 3A receptors

In spite of extensive efforts over decades an experimentally-derived structure of full-length eukaryotic pentameric ligand-gated ion channels (pLGICs) is still lacking. These pharmaceutically highly-relevant channels contain structurally well-conserved and characterized extracellular and transmembra...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pandhare, Akash, Grozdanov, Petar N., Jansen, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820698/
https://ncbi.nlm.nih.gov/pubmed/27045630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23921
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