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The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors

The FDA-approved antidepressant and smoking cessation drug bupropion is known to inhibit dopamine and norepinephrine reuptake transporters, as well as nicotinic acetylcholine receptors (nAChRs) which are cation-conducting members of the Cys-loop superfamily of ion channels, and more broadly pentamer...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Pandhare, Akash, Pappu, Aneesh Satya, Wilms, Henrik, Blanton, Michael Paul, Jansen, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148637/
https://ncbi.nlm.nih.gov/pubmed/27671323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.09.021
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