Structural Sensitivity of a Prokaryotic Pentameric Ligand-gated Ion Channel to Its Membrane Environment

Although the activity of the nicotinic acetylcholine receptor (nAChR) is exquisitely sensitive to its membrane environment, the underlying mechanisms remain poorly defined. The homologous prokaryotic pentameric ligand-gated ion channel, Gloebacter ligand-gated ion channel (GLIC), represents an excel...

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Main Authors: Labriola, Jonathan M., Pandhare, Akash, Jansen, Michaela, Blanton, Michael P., Corringer, Pierre-Jean, Baenziger, John E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630840/
https://ncbi.nlm.nih.gov/pubmed/23463505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458133
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