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Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of drugs – method development and application to magnesium in sheep
BACKGROUND: There have been few reports of pharmacokinetic models that have been linked to models of the cardiovascular system. Such models could predict the cardiovascular effects of a drug under a variety of circumstances. Limiting factors may be the lack of a suitably simple cardiovascular model,...
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| Natura: | Artigo |
| Lingua: | Inglês |
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BioMed Central
2005
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC555767/ https://ncbi.nlm.nih.gov/pubmed/15760466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-5-5 |
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