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In vitro pharmacokinetic/pharmacodynamic models in anti-infective drug development: focus on TB

For rapid anti-tuberculosis (TB) drug development in vitro pharmacokinetic/pharmacodynamic (PK/PD) models are useful in evaluating the direct interaction between the drug and the bacteria, thereby guiding the selection of candidate compounds and the optimization of their dosing regimens. Utilizing i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vaddady, Pavan K, Lee, Richard E, Meibohm, Bernd
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042695/
https://ncbi.nlm.nih.gov/pubmed/21359155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.10.224
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