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In vitro pharmacokinetic/pharmacodynamic models in anti-infective drug development: focus on TB

For rapid anti-tuberculosis (TB) drug development in vitro pharmacokinetic/pharmacodynamic (PK/PD) models are useful in evaluating the direct interaction between the drug and the bacteria, thereby guiding the selection of candidate compounds and the optimization of their dosing regimens. Utilizing i...

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Main Authors: Vaddady, Pavan K, Lee, Richard E, Meibohm, Bernd
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042695/
https://ncbi.nlm.nih.gov/pubmed/21359155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.10.224
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