Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of drugs – method development and application to magnesium in sheep

Por Upton, Richard N, Ludbrook, Guy L
Publicado em 2005

Perfusion–diffusion compartmental models describe cerebral helium kinetics at high and low cerebral blood flows in sheep

Por Doolette, David J, Upton, Richard N, Grant, Cliff
Publicado em 2005

A pharmacokinetic model for L-carnitine in patients receiving haemodialysis

Por Fornasini, Gianfranco, Upton, Richard N, Evans, Allan M
Publicado em 2007

Dashboard Systems: Implementing Pharmacometrics from Bench to Bedside

Por Mould, Diane R., Upton, Richard N., Wojciechowski, Jessica
Publicado em 2014

Translational pain research: Evaluating analgesic effect in experimental visceral pain models

Por Olesen, Anne Estrup, Andresen, Trine, Christrup, Lona Louring, Upton, Richard N
Publicado em 2009

Population Pharmacokinetic Modeling of Itraconazole and Hydroxyitraconazole for Oral SUBA-Itraconazole and Sporanox Capsule Formulations in Healthy Subjects in Fed and Fasted State...

Por Abuhelwa, Ahmad Y., Foster, David J. R., Mudge, Stuart, Hayes, David, Upton, Richard N.
Publicado no Antimicrob Agents Chemother (2015)

A population model of early rheumatoid arthritis disease activity during treatment with methotrexate, sulfasalazine and hydroxychloroquine

Por Wojciechowski, Jessica, Wiese, Michael D, Proudman, Susanna M, Foster, David J R, Upton, Richard N
Publicado no Br J Clin Pharmacol (2015)

A model‐based evaluation of single metrics for discriminating changes in rheumatoid arthritis disease activity

Por Wojciechowski, Jessica, Wiese, Michael D., Proudman, Susanna M., Foster, David J. R., Upton, Richard N.
Publicado no Br J Clin Pharmacol (2016)

Blood–brain equilibration kinetics of levo-α-acetyl-methadol using a chronically instrumented sheep preparation

Por Foster, David J R, Jensen, Mette L, Upton, Richard N, Somogyi, Andrew A, Grant, Cliff, Martinez, Allison
Publicado em 2005

Population Pharmacokinetic Model of Doxycycline Plasma Concentrations Using Pooled Study Data

Por Hopkins, Ashley M., Wojciechowski, Jessica, Abuhelwa, Ahmad Y., Mudge, Stuart, Upton, Richard N., Foster, David J. R.
Publicado no Antimicrob Agents Chemother (2017)

Genetic polymorphism of CYP1A2 but not total or free teriflunomide concentrations is associated with leflunomide cessation in rheumatoid arthritis

Por Hopkins, Ashley M., Wiese, Michael D., Proudman, Susanna M., O'Doherty, Catherine E., Upton, Richard N., Foster, David J. R.
Publicado no Br J Clin Pharmacol (2015)

Pharmacokinetics of tramadol after subcutaneous administration in a critically ill population and in a healthy cohort

Por Dooney, Neil M, Sundararajan, Krishnaswamy, Ramkumar, Tharapriya, Somogyi, Andrew A, Upton, Richard N, Ong, Jennifer, O’Connor, Stephanie N, Chapman, Marianne J, Ludbrook, Guy L
Publicado em 2014