A model‐based evaluation of single metrics for discriminating changes in rheumatoid arthritis disease activity

AIMS: Composite indices for quantifying rheumatoid arthritis (RA) disease activity such as the 28‐joint disease activity score (DAS28) are comprised of single parameters (‘metrics’) in various combinations. Population modelling methods were used to evaluate single metrics for their ability to reflec...

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Udgivet i:Br J Clin Pharmacol
Main Authors: Wojciechowski, Jessica, Wiese, Michael D., Proudman, Susanna M., Foster, David J. R., Upton, Richard N.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Pharmacodynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876190/
https://ncbi.nlm.nih.gov/pubmed/26810813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12891
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