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Pharmacokinetics/pharmacodynamics and the stages of drug development: Role of modeling and simulation
Pharmacokinetic (PK) and pharmacodynamic (PD) modeling and simulation (M&S) are well-recognized powerful tools that enable effective implementation of the learn-and-confirm paradigm in drug development. The impact of PK/PD M&S on decision making and drug development risk management is depend...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751257/ https://ncbi.nlm.nih.gov/pubmed/16353932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070355 |
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