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Pharmacokinetics and Pharmacodynamics Modeling and Simulation Systems to Support the Development and Regulation of Liposomal Drugs

Liposomal formulations have been developed to improve the therapeutic index of encapsulated drugs by altering the balance of on- and off-targeted distribution. The improved therapeutic efficacy of liposomal drugs is primarily attributed to enhanced distribution at the sites of action. The targeted d...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: He, Hua, Yuan, Dongfen, Wu, Yun, Cao, Yanguang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471205/
https://ncbi.nlm.nih.gov/pubmed/30866479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11030110
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