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Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development: Part 3—Introduction to Pharmacodynamic Modeling Methods

Population pharmacodynamic (PD) models describe the time course of drug effects, relating exposure to response, and providing a more robust understanding of drug action than single assessments. PD models can test alternative dose regimens through simulation, allowing for informed assessment of poten...

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Detalhes bibliográficos
Main Authors: Upton, R N, Mould, D R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917320/
https://ncbi.nlm.nih.gov/pubmed/24384783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2013.71
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