In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations()

Nociceptin/Orphanin FQ (N/OFQ) regulates several biological functions via selective activation of the N/OFQ receptor (NOP). In this study novel nonpeptide NOP ligands were characterized in vitro in receptor binding and [(35)S]GTPγS stimulated binding in membranes of cells expressing human NOP and cl...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Pharmacol
Egile Nagusiak: Ferrari, Federica, Cerlesi, Maria Camilla, Malfacini, Davide, Asth, Laila, Gavioli, Elaine C., Journigan, Blair V., Kamakolanu, Uma Gayathri, Meyer, Michael E., Yasuda, Dennis, Polgar, Willma E., Rizzi, Anna, Guerrini, Remo, Ruzza, Chiara, Zaveri, Nurulain T., Calo, Girolamo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555400/
https://ncbi.nlm.nih.gov/pubmed/27780725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.10.025
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