Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

The aim of the study was to investigate the in vitro and in vivo pharmacological profile of cebranopadol, a novel agonist for opioid and nociceptin/orphanin FQ (N/OFQ) receptors (NOP). In vitro cebranopadol was assayed in calcium mobilization studies in cells coexpressing NOP or opioid receptors and...

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Dettagli Bibliografici
Pubblicato in:Pharmacol Res Perspect
Autori principali: Rizzi, Anna, Cerlesi, Maria Camilla, Ruzza, Chiara, Malfacini, Davide, Ferrari, Federica, Bianco, Sara, Costa, Tommaso, Guerrini, Remo, Trapella, Claudio, Calo', Girolamo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242173/
https://ncbi.nlm.nih.gov/pubmed/28116100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.247
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