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Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

The aim of the study was to investigate the in vitro and in vivo pharmacological profile of cebranopadol, a novel agonist for opioid and nociceptin/orphanin FQ (N/OFQ) receptors (NOP). In vitro cebranopadol was assayed in calcium mobilization studies in cells coexpressing NOP or opioid receptors and...

詳細記述

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書誌詳細
出版年:Pharmacol Res Perspect
主要な著者: Rizzi, Anna, Cerlesi, Maria Camilla, Ruzza, Chiara, Malfacini, Davide, Ferrari, Federica, Bianco, Sara, Costa, Tommaso, Guerrini, Remo, Trapella, Claudio, Calo', Girolamo
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242173/
https://ncbi.nlm.nih.gov/pubmed/28116100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.247
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