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Molecular origin of constant m-values, denatured state collapse, and residue-dependent transition midpoints in globular proteins
Experiments show that for many two state folders the free energy of the native state ΔG(ND)([C]) changes linearly as the denaturant concentration [C] is varied. The slope, [Formula: see text] , is nearly constant. According to the Transfer Model, the m-value is associated with the difference in the...
Shranjeno v:
| izdano v: | Biochemistry |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551902/ https://ncbi.nlm.nih.gov/pubmed/19278261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8021119 |
| Oznake: |
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