Collapse kinetics and chevron plots from simulations of denaturant-dependent folding of globular proteins

Quantitative description of how proteins fold under experimental conditions remains a challenging problem. Experiments often use urea and guanidinium chloride to study folding whereas the natural variable in simulations is temperature. To bridge the gap, we use the molecular transfer model that comb...

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Bibliografiske detaljer
Main Authors: Liu, Zhenxing, Reddy, Govardhan, O’Brien, Edward P., Thirumalai, D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093460/
https://ncbi.nlm.nih.gov/pubmed/21512127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019500108
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