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Metastability of the folded states of globular proteins.

The possibility that several metastable minima exist in which the folded forms of a polypeptide chain have similar structural characteristics but different energies is suggested. The validity of this hypothesis is illustrated with the aid of simulation methods on a model protein that folds into a be...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Honeycutt, J D, Thirumalai, D
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2333297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3526
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