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Metastability of the folded states of globular proteins.

The possibility that several metastable minima exist in which the folded forms of a polypeptide chain have similar structural characteristics but different energies is suggested. The validity of this hypothesis is illustrated with the aid of simulation methods on a model protein that folds into a be...

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Detalhes bibliográficos
Main Authors: Honeycutt, J D, Thirumalai, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53934/
https://ncbi.nlm.nih.gov/pubmed/2333297
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