Metastability of the folded states of globular proteins.
The possibility that several metastable minima exist in which the folded forms of a polypeptide chain have similar structural characteristics but different energies is suggested. The validity of this hypothesis is illustrated with the aid of simulation methods on a model protein that folds into a be...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2333297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3526 |
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