Cooperativity in protein-folding kinetics.
How does a protein find its native state without a globally exhaustive search? We propose the "HZ" (hydrophobic zipper) hypothesis: hydrophobic contacts act as constraints that bring other contacts into spatial proximity, which then further constrain and zip up the next contacts, etc. In contrast to...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7680482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.5.1942 |
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