Cooperativity in protein-folding kinetics.

How does a protein find its native state without a globally exhaustive search? We propose the "HZ" (hydrophobic zipper) hypothesis: hydrophobic contacts act as constraints that bring other contacts into spatial proximity, which then further constrain and zip up the next contacts, etc. In contrast to...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Dill, K A, Fiebig, K M, Chan, H S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7680482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.5.1942
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