Evolution-like selection of fast-folding model proteins.
We propose an algorithm providing sequences of model proteins with rapid folding into a given target (native) conformation. This algorithm is applied to a chain of 27 residues on a cubic lattice. It generates sequences with folding 2 orders of magnitude faster than that of the practically random sta...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7877968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1282 |
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