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Evolution-like selection of fast-folding model proteins.

We propose an algorithm providing sequences of model proteins with rapid folding into a given target (native) conformation. This algorithm is applied to a chain of 27 residues on a cubic lattice. It generates sequences with folding 2 orders of magnitude faster than that of the practically random sta...

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Dettagli Bibliografici
Autori principali: Gutin, A M, Abkevich, V I, Shakhnovich, E I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC42503/
https://ncbi.nlm.nih.gov/pubmed/7877968
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