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Denaturant-dependent folding of GFP

We use molecular simulations using a coarse-grained model to map the folding landscape of Green Fluorescent Protein (GFP), which is extensively used as a marker in cell biology and biotechnology. Thermal and Guanidinium chloride (GdmCl) induced unfolding of a variant of GFP, without the chromophore,...

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Sonraí Bibleagrafaíochta
Main Authors: Reddy, Govardhan, Liu, Zhenxing, Thirumalai, D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497794/
https://ncbi.nlm.nih.gov/pubmed/22778437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201808109
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