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The innate cytokines IL-25, IL-33 and TSLP cooperate in the induction of ILC2 expansion and mucous metaplasia in rhinovirus-infected immature mice
BACKGROUND: Early-life respiratory viral infection is a risk factor for asthma development. Rhinovirus (RV) infection of six-day old but not mature mice causes mucous metaplasia and airway hyperresponsiveness which is associated with expansion of lung type 2 innate lymphoid cells (ILC2s) and depende...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548608/ https://ncbi.nlm.nih.gov/pubmed/28701507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700216 |
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