The innate cytokines IL-25, IL-33 and TSLP cooperate in the induction of ILC2 expansion and mucous metaplasia in rhinovirus-infected immature mice

BACKGROUND: Early-life respiratory viral infection is a risk factor for asthma development. Rhinovirus (RV) infection of six-day old but not mature mice causes mucous metaplasia and airway hyperresponsiveness which is associated with expansion of lung type 2 innate lymphoid cells (ILC2s) and depende...

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Han, Mingyuan, Rajput, Charu, Hong, Jun Y., Lei, Jing, Hinde, Joanna L., Wu, Qian, Bentley, J. Kelley, Hershenson, Marc B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548608/
https://ncbi.nlm.nih.gov/pubmed/28701507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700216
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