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Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness via IL-25 and ILC2s

BACKGROUND: Early-life human rhinovirus (RV) infection has been linked to asthma development in high risk infants and children. Nevertheless, the role of RV infection in the initiation of asthma remains unclear. OBJECTIVE: We hypothesized that, in contrast to infection of mature BALB/c mice, neonata...

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Detalhes bibliográficos
Main Authors: Hong, Jun Young, Bentley, J. Kelley, Chung, Yutein, Lei, Jing, Steenrod, Jessica M., Chen, Qiang, Sajjan, Uma S., Hershenson, Marc B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119851/
https://ncbi.nlm.nih.gov/pubmed/24910174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.04.020
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