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IL-1β prevents ILC2 expansion, type 2 cytokine secretion and mucus metaplasia in response to early-life rhinovirus infection in mice

BACKGROUND: Early-life wheezing-associated respiratory infection with human rhinovirus (RV) is associated with asthma development. RV infection of six day-old immature mice causes mucous metaplasia and airway hyperresponsiveness which is associated with the expansion of IL-13-producing type 2 innate...

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Bibliografski detalji
Izdano u:Allergy
Glavni autori: Han, Mingyuan, Ishikawa, Tomoko, Bermick, Jennifer R., Rajput, Charu, Lei, Jing, Goldsmith, Adam M., Jarman, Caitlin R., Lee, Julie, Bentley, J. Kelley, Hershenson, Marc B.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066359/
https://ncbi.nlm.nih.gov/pubmed/32086822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14241
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