Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice

The coincidences between Alzheimer’s disease (AD) and type 2 diabetes mellitus (T2DM) are so compelling that it is attractive to speculate that diabetic conditions might aggravate AD pathologies by calcium dysfunction, although the understanding of the molecular mechanisms involved remains elusive....

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Zhang, Shuai, Chai, Rui, Yang, Ying-Ying, Guo, Shi-Qi, Wang, Shan, Guo, Tian, Xu, Shuang-Feng, Zhang, Yan-Hui, Wang, Zhan-You, Guo, Chuang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546429/
https://ncbi.nlm.nih.gov/pubmed/28467789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17116
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