Rescue of cognitive deficits in APP/PS1 mice by accelerating the aggregation of β-amyloid peptide

BACKGROUND: Brain amyloid deposition is one of the main pathological characteristics of Alzheimer’s disease (AD). Soluble oligomers formed during the process that causes β-amyloid (Aβ) to aggregate into plaques are considered to have major neurotoxicity. Currently, drug development for the treatment...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Zhang, Jian-Xiang, Lai, Yi-Hui, Mi, Pan-Ying, Dai, Xue-Ling, Zhang, Ran, Zhang, Zhan-Jun, Zhang, Shu-Juan, Zhang, Xi-Wen, Zhang, Xi-Yan, Yang, Bing-Yu, Cui, Dong-Mei, Zhang, Chen, Zhao, Chang-Qi, Dou, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918606/
https://ncbi.nlm.nih.gov/pubmed/31847879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0560-6
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