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mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3

Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proliferation,...

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Foilsithe in:Sci Rep
Main Authors: Liu, Yanli, Xu, Hanchun, An, Meixia
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544690/
https://ncbi.nlm.nih.gov/pubmed/28779179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07844-y
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