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mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3

Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proliferation,...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Liu, Yanli, Xu, Hanchun, An, Meixia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544690/
https://ncbi.nlm.nih.gov/pubmed/28779179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07844-y
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