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mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3

Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proliferation,...

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Pubblicato in:Sci Rep
Autori principali: Liu, Yanli, Xu, Hanchun, An, Meixia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544690/
https://ncbi.nlm.nih.gov/pubmed/28779179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07844-y
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