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mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3

Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proliferation,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Yanli, Xu, Hanchun, An, Meixia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544690/
https://ncbi.nlm.nih.gov/pubmed/28779179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07844-y
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