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PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation
Defects in the PEX5 gene impair the import of peroxisomal matrix proteins, leading to nonfunctional peroxisomes and other associated pathological defects such as Zellweger syndrome. Although PEX5 regulates autophagy process in a stress condition, the mechanisms controlling autophagy by PEX5 under nu...
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| Pubblicato in: | Exp Mol Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5938032/ https://ncbi.nlm.nih.gov/pubmed/29622767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-017-0007-8 |
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