Regulation of TFEB and V-ATPases by mTORC1

Mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is an important, highly conserved, regulator of cell growth. Ancient among the signals that regulate mTORC1 are nutrients. Amino acids direct mTORC1 to the surface of the late endosome/lysosome, where mTORC1 becomes receptive to other inputs. H...

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Autores principales: Peña-Llopis, Samuel, Vega-Rubin-de-Celis, Silvia, Schwartz, Jacob C, Wolff, Nicholas C, Tran, Tram Anh T, Zou, Lihua, Xie, Xian-Jin, Corey, David R, Brugarolas, James
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160667/
https://ncbi.nlm.nih.gov/pubmed/21804531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.257
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