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Multistep regulation of TFEB by MTORC1
The master regulator of lysosome biogenesis, TFEB, is regulated by MTORC1 through phosphorylation at S211, and a S211A mutation increases nuclear localization. However, TFEB(S211A) localizes diffusely in both cytoplasm and nucleus and, as we show, retains regulation by MTORC1. Here, we report that e...
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| Publicado no: | Autophagy |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5361595/ https://ncbi.nlm.nih.gov/pubmed/28055300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1271514 |
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