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Targeting mTORC2 component rictor inhibits cell proliferation and promotes apoptosis in gastric cancer

The mammalian target of rapamycin (mTOR) kinase acts downstream of phosphoinositide 3-kinase/Akt and plays an important role in tumor growth and progression of gastric cancer. It is well characterized that mTOR complex1 (mTORC1) controls cell metabolism and proliferation, whereas the contribution of...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Bian, Yu-Hai, Xu, Jia, Zhao, Wen-Yi, Zhang, Zi-Zhen, Tu, Lin, Cao, Hui, Zhang, Zhi-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622274/
https://ncbi.nlm.nih.gov/pubmed/28979705
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