Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models

Mammalian Target of Rapamycin complex 2 (mTORC2) and its regulatory component Rapamycin-insensitive companion of mTOR (RICTOR) are increasingly recognized as important players in human cancer development and progression. However, the role of RICTOR in human pancreatic ductal adenocarcinoma (PDAC) is...

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Vydáno v:Oncotarget
Hlavní autoři: Schmidt, Katharina M., Hellerbrand, Claus, Ruemmele, Petra, Michalski, Christoph W., Kong, Bo, Kroemer, Alexander, Hackl, Christina, Schlitt, Hans J., Geissler, Edward K., Lang, Sven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421865/
https://ncbi.nlm.nih.gov/pubmed/28445935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15524
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