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The mTORC2 Component Rictor Contributes to Cisplatin Resistance in Human Ovarian Cancer Cells

Resistance to cisplatin-based therapy is a major cause of treatment failure in human ovarian cancer. A better understanding of the mechanisms of cisplatin resistance will offer new insights for novel therapeutic strategies for this deadly disease. Akt and p53 are determinants of cisplatin sensitivit...

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Detalhes bibliográficos
Main Authors: Im-aram, Akechai, Farrand, Lee, Bae, Seung-Min, Song, Gwonhwa, Song, Yong Sang, Han, Jae Yong, Tsang, Benjamin K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781115/
https://ncbi.nlm.nih.gov/pubmed/24086535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075455
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