Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors

Central to cellular proliferative, survival, and metabolic responses is the serine/threonine kinase mTOR, which is activated in many human cancers. mTOR is present in distinct complexes that are either modulated by AKT (mTORC1) or are upstream and regulatory of it (mTORC2). Governance of mTORC2 acti...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Lee, Dongjun, Sykes, Stephen M., Kalaitzidis, Demetrios, Lane, Andrew A., Kfoury, Youmna, Raaijmakers, Marc H.G.P., Wang, Ying-Hua, Armstrong, Scott A., Scadden, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235746/
https://ncbi.nlm.nih.gov/pubmed/25418727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.011
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