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Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors

Central to cellular proliferative, survival, and metabolic responses is the serine/threonine kinase mTOR, which is activated in many human cancers. mTOR is present in distinct complexes that are either modulated by AKT (mTORC1) or are upstream and regulatory of it (mTORC2). Governance of mTORC2 acti...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Lee, Dongjun, Sykes, Stephen M., Kalaitzidis, Demetrios, Lane, Andrew A., Kfoury, Youmna, Raaijmakers, Marc H.G.P., Wang, Ying-Hua, Armstrong, Scott A., Scadden, David T.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235746/
https://ncbi.nlm.nih.gov/pubmed/25418727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.011
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