Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis()()

Mammalian target of rapamycin complex 2 (mTORC2) with its pivotal component rapamycin-insensitive companion of mTOR (RICTOR) is the major regulator of AKT phosphorylation and is increasingly implicated in tumor growth and progression. In cutaneous melanoma, an extremely aggressive and highly metasta...

詳細記述

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書誌詳細
出版年:Neoplasia
主要な著者: Schmidt, Katharina M., Dietrich, Peter, Hackl, Christina, Guenzle, Jessica, Bronsert, Peter, Wagner, Christine, Fichtner-Feigl, Stefan, Schlitt, Hans J., Geissler, Edward K., Hellerbrand, Claus, Lang, Sven A.
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press 2018
主題:
Original article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224335/
https://ncbi.nlm.nih.gov/pubmed/30404068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.10.001
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