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Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis()()
Mammalian target of rapamycin complex 2 (mTORC2) with its pivotal component rapamycin-insensitive companion of mTOR (RICTOR) is the major regulator of AKT phosphorylation and is increasingly implicated in tumor growth and progression. In cutaneous melanoma, an extremely aggressive and highly metasta...
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| 發表在: | Neoplasia |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Neoplasia Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224335/ https://ncbi.nlm.nih.gov/pubmed/30404068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.10.001 |
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