The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.

The v-sis transforming gene encodes the woolly monkey homologue of human platelet-derived growth factor (PDGF) polypeptide 2. After its synthesis on membrane bound polyribosomes, the glycosylated precursor dimerizes in the endoplasmic reticulum and travels through the Golgi apparatus. At the cell pe...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Robbins, K C, Leal, F, Pierce, J H, Aaronson, S A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1985
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Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554418/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2992941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb03851.x
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