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Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors.

v-sis represents a prototype for the class of oncogenes that encode growth factors. Whether its platelet-derived growth factor (PDGF)-like product functionally activates its receptors within the cell or at the cell surface has potential implications in efforts to intervene with the v-sis-transformed...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Fleming, T P, Matsui, T, Molloy, C J, Robbins, K C, Aaronson, S A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC298215/
https://ncbi.nlm.nih.gov/pubmed/2813378
Etiketler: Etiketle
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