The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.

The v-sis transforming gene encodes the woolly monkey homologue of human platelet-derived growth factor (PDGF) polypeptide 2. After its synthesis on membrane bound polyribosomes, the glycosylated precursor dimerizes in the endoplasmic reticulum and travels through the Golgi apparatus. At the cell pe...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Robbins, K C, Leal, F, Pierce, J H, Aaronson, S A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2992941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb03851.x
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