The phenotypic characteristics of simian sarcoma virus-transformed human fibroblasts suggest that the v-sis gene product acts solely as a PDGF receptor agonist in cell transformation.

Antzeko izenburuak

• Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.
  nork: Betsholtz, C, et al.
  Argitaratua: (1986)
• Platelet-derived growth factor agonist activity of a secreted form of the v-sis oncogene product.
  nork: Johnsson, A, et al.
  Argitaratua: (1985)
• Rat skeletal myoblasts and arterial smooth muscle cells express the gene for the A chain but not the gene for the B chain (c-sis) of platelet-derived growth factor (PDGF) and produce a PDGF-like protein.
  nork: Sejersen, T, et al.
  Argitaratua: (1986)
• Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation.
  nork: Hermansson, M, et al.
  Argitaratua: (1988)
• Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor.
  nork: Westermark, B, et al.
  Argitaratua: (1986)