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Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

Forkhead box class O (FOXO) proteins are transcription factors that function downstream of the PTEN tumor suppressor and directly control the expression of genes involved in apoptosis, cell cycle progression, and stress responses. In the present study, we show that FOXO1 interacts with four and a ha...

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Hlavní autoři: Yang, Yonghua, Hou, Huayan, Haller, Edward M, Nicosia, Santo V, Bai, Wenlong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC554122/
https://ncbi.nlm.nih.gov/pubmed/15692560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600570
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